the builder for the CR10S S5 will not compile just as it is
this is the error
rror: static assertion failed: PREHEAT_2_TEMP_HOTEND (250) must be less than HEATER_0_MAXTEMP (255) - 15.
This is due to a tightening of sanity checking of configurations.
In essence, all max temperatures need to be below both the max temps, and the thermistor max temp specifications.
This shows that the preset temperature + 15c (overshoot detection) is higher than the max temperature that is set for the hotend.
You can either increase the max temp (assuming that keeps the thermistor within specifications) or reduce the preset 2 temperature from 250 to 240 or lower.